CHEMICAL, PHARMACEUTICAL AND BIOLOGICAL DEGRADATION BIBLIOGRAPHY Vitamin chemistry REF
نویسنده
چکیده
L-ascorbic acid is found in equilibrium with its oxidative degradation product, L-dehydroascorbic acid, which is used in the body in the same way as ascorbic acid. L-dehydroascorbic acid has its maximum stability at room temperature at pH 2-3 and it will at pH values above 7 degrade irreversibly during formation of 2,3-diketogulonic acid which shows no vitamin C activity. Finally, at high pH values 2,3-diketogulonic acid can degrade to threonic, xylonic and oxalic acid. Therefore, at pH values above 7 a reaction will occur leading to a net degradation of the ascorbic acid causing a formation of these degradation products.
منابع مشابه
Scientific Correspondence Chemical Genetic Approaches to Plant Biology
Synthetic chemistry and plant biology intersect in myriad ways. To date, however, the overlap of research methods between these two fields is limited. Outside of the agrochemical industry, most synthetic chemists simply view plants as sources of diverse and structurally complex organic molecules (i.e. natural products), frequently with exquisite biological activities. Little knowledge of plant ...
متن کاملProduction and on-line acetylcholinesterase bioactivity profiling of chemical and biological degradation products of tacrine.
The present paper describes a methodology for rapid assessment of chemical and biological degradation products of tacrine and their bioactivity for acetylcholinesterase (AChE). Analysis was achieved by utilizing liquid chromatography coupled to parallel high resolution mass spectrometry and an on-line continuous-flow AChE bioassay for biochemical detection. Key advantage of the strategy describ...
متن کاملAnalytical approaches to determination of carnitine in biological materials, foods and dietary supplements.
l-Carnitine is a vitamin-like amino acid derivative, which is an essential factor in fatty acid metabolism as acyltransferase cofactor and in energy production processes, such as interconversion in the mechanisms of regulation of cetogenesis and termogenesis, and it is also used in the therapy of primary and secondary deficiency, and in other diseases. The determination of carnitine and acyl-ca...
متن کاملVoltammetric determination of glutathione in pharmaceutical and biological samples using multiwall carbon nanotubes paste electrode in the presence of rutin as a mediator
A new sensitive, selective and nonexpensive electrochemical sensor was developed for electrocatalyticdetermination of glutathione (GSH)in pharmaceutical and biological samples. GSH is a tripeptide thiol present in all eukaryotic and probiotic cells. A voltammetric studyof GSH has been carried out at the surface of carbon paste electrode modified with multiwall carbon nanotubes(MWCNTPE) in the p...
متن کاملBioremediation of pharmaceutical industrial effluent by organisms screened from effluent discharged soil
Two bacterial strains were isolated from pharmaceutical effluents discharged soil. The samples were identified as Klebsiella pneumonia and Pseudomonas aeruginosa the biological degradation was carried on two bacterial isolates separately added to pharmaceutical effluent water. After proper interval were analysed the physic chemical parameters such as pH, Turbidity, Chemical oxygen demand (COD),...
متن کامل